Antiviral Drug Discovery (AViDD) Centers
The nine AViDD Centers listed below will conduct innovative, multidisciplinary research to develop candidate COVID-19 antivirals, especially those that can be taken in an outpatient setting, as well as antivirals targeting specific viral families with high potential to cause a pandemic in the future. These include paramyxoviruses, bunyaviruses, togaviruses, filoviruses (including Ebola viruses and Marburg virus), picornaviruses (including enteroviruses and other cold-causing viruses), and flaviviruses (including the viruses that cause yellow fever, dengue and Zika).
AI-Driven Structure-Enabled Antiviral Platform (ASAP)
Principal Investigators: John Chodera, Ph.D.; Benjamin Perry, Ph.D.; Alpha Lee, Ph.D.
Institutes: Sloan Kettering Institute of Cancer Research; Drugs for Neglected Diseases Initiative; PostEra, Inc.
Award #: U19AI171399
Antiviral Countermeasures Development Center (AC/DC)
Principal Investigators: George Painter, Ph.D.; Richard Plemper, Ph.D.
Institutes: Emory University; Georgia State University
Award #: U19AI171403
Center for Antiviral Medicines & Pandemic Preparedness (CAMPP)
Principal Investigators: Sumit Chanda, Ph.D.; Arnab Chatterjee, Ph.D; Adolfo García-Sastre, Ph.D.
Institutes: Scripps Research Institute; Calibr; Icahn School of Medicine at Mt.Sinai
Award #: U19AI171443
Development of Outpatient Antiviral Cocktails against SARS-CoV-2 and other Potential Pandemic RNA Viruses
Principal Investigator: Jeffrey Glenn, M.D., Ph.D.
Institute: Stanford University
Award #: U19AI171421
Metropolitan AntiViral Drug Accelerator (MAVDA)
Principal Investigators: David Perlin, Ph.D.; Charles Rice, Ph.D.
Institute: Hackensack University Medical Center; The Rockefeller University
Award #: U19AI171401
Midwest AViDD Center
Principal Investigators: Reuben Harris, Ph.D.; Fang Li, Ph.D.
Institute: University of Minnesota
Award #: U19AI171954
QCRG Pandemic Response Program
Principal Investigator: Nevan Krogan, Ph.D.
Institute: University of California, San Francisco
Award #: U19AI171110
Rapidly Emerging Antiviral Drug Development Initiative – AViDD Center (READDI-AC)
Principal Investigators: Ralph Baric, Ph.D.; Timothy Willson, Ph.D.
Institute: The University of North Carolina at Chapel Hill
Award #: U19AI171292
UTMB-Novartis Alliance for Pandemic Preparedness
Principal Investigators: Pei-Yong Shi, Ph.D.; Thierry Diagana, Ph.D.
Institutes: The University of Texas Medical Branch; Novartis Institute of Biomedical Research, Inc.
Award #: U19AI171413